The role of radiation therapy in melanoma.
Identifieur interne : 002403 ( Main/Exploration ); précédent : 002402; suivant : 002404The role of radiation therapy in melanoma.
Auteurs : Jacqueline Oxenberg [États-Unis] ; John M. Kane [États-Unis]Source :
- The Surgical clinics of North America [ 1558-3171 ] ; 2014.
Descripteurs français
- KwdFr :
- Antinéoplasiques (usage thérapeutique), Facteurs de risque, Humains, Interférons (usage thérapeutique), Lymphadénectomie, Mélanome (), Mélanome (radiothérapie), Métastase lymphatique, Radiothérapie adjuvante (), Récidive tumorale locale (), Récidive tumorale locale (radiothérapie), Résultat thérapeutique, Traitement médicamenteux adjuvant, Tumeurs cutanées (), Tumeurs cutanées (radiothérapie), Tumeurs de l'anus (radiothérapie), Tumeurs de la tête et du cou (radiothérapie), Tumeurs du rectum (radiothérapie).
- MESH :
- radiothérapie : Mélanome, Récidive tumorale locale, Tumeurs cutanées, Tumeurs de l'anus, Tumeurs de la tête et du cou, Tumeurs du rectum.
- usage thérapeutique : Antinéoplasiques, Interférons.
- Facteurs de risque, Humains, Lymphadénectomie, Mélanome, Métastase lymphatique, Radiothérapie adjuvante, Récidive tumorale locale, Résultat thérapeutique, Traitement médicamenteux adjuvant, Tumeurs cutanées.
English descriptors
- KwdEn :
- Antineoplastic Agents (therapeutic use), Anus Neoplasms (radiotherapy), Chemotherapy, Adjuvant, Head and Neck Neoplasms (radiotherapy), Humans, Interferons (therapeutic use), Lymph Node Excision, Lymphatic Metastasis, Melanoma (radiotherapy), Melanoma (surgery), Neoplasm Recurrence, Local (radiotherapy), Neoplasm Recurrence, Local (surgery), Radiotherapy, Adjuvant (methods), Rectal Neoplasms (radiotherapy), Risk Factors, Skin Neoplasms (radiotherapy), Skin Neoplasms (surgery), Treatment Outcome.
- MESH :
- chemical , therapeutic use : Antineoplastic Agents, Interferons.
- methods : Radiotherapy, Adjuvant.
- radiotherapy : Anus Neoplasms, Head and Neck Neoplasms, Melanoma, Neoplasm Recurrence, Local, Rectal Neoplasms, Skin Neoplasms.
- surgery : Melanoma, Neoplasm Recurrence, Local, Skin Neoplasms.
- Chemotherapy, Adjuvant, Humans, Lymph Node Excision, Lymphatic Metastasis, Risk Factors, Treatment Outcome.
Abstract
Although melanoma was historically thought to be radiation resistant, there are limited data to support the use of adjuvant radiation therapy for certain situations at increased risk for locoregional recurrence. High-risk primary tumor features include thickness, ulceration, certain anatomic locations, satellitosis, desmoplastic/neurotropic features, and head and neck mucosal and anorectal melanoma. Lentigo maligna can be effectively treated with either adjuvant or definitive radiation therapy. Some retrospective and prospective randomized studies support the use of adjuvant radiation to improve regional control after lymph node dissection for high-risk nodal metastatic disease. Consensus on the optimal radiation doses and fractionation is lacking.
DOI: 10.1016/j.suc.2014.07.006
PubMed: 25245966
Affiliations:
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Kane</name><affiliation wicri:level="2"><nlm:affiliation>Melanoma-Sarcoma Service, Department of Surgical Oncology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. 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Kane</name><affiliation wicri:level="2"><nlm:affiliation>Melanoma-Sarcoma Service, Department of Surgical Oncology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. 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High-risk primary tumor features include thickness, ulceration, certain anatomic locations, satellitosis, desmoplastic/neurotropic features, and head and neck mucosal and anorectal melanoma. Lentigo maligna can be effectively treated with either adjuvant or definitive radiation therapy. Some retrospective and prospective randomized studies support the use of adjuvant radiation to improve regional control after lymph node dissection for high-risk nodal metastatic disease. Consensus on the optimal radiation doses and fractionation is lacking.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Oxenberg, Jacqueline" sort="Oxenberg, Jacqueline" uniqKey="Oxenberg J" first="Jacqueline" last="Oxenberg">Jacqueline Oxenberg</name></region><name sortKey="Kane, John M" sort="Kane, John M" uniqKey="Kane J" first="John M" last="Kane">John M. 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